Wednesday, March 7, 2012

Eye Pigment, Colonoscopy & Colon Cancer

Retina Layers
What could the need to have a colonoscopy possibly have to do with eye pigment in the Retina and early detection of colon cancer you ask? The Retinal Pigmented Epithelium (RPE) is a pigmented layer of the Retina which can sometimes be thicker than normal at birth-or “hypertrophic”. When found, areas of Retinal Pigmented Epithelial (RPE) Hypertrophy usually do not cause any vision problems or symptoms and are typically found during routine eye examinations. Congenital Retinal Pigment Epithelial Hypertrophy (CHRPE) is usually found before patients reach 30 years of age and although they may enlarge with time they usually do not lead to malignancies like colon cancer. However, there is an association between people with Gardner's Syndrome-Familial Colonic Polyposes-or polyps of the colon, and CHRPE. If your eye doctor has told you that you have Congenital Retinal Pigment Epithelial Hypertrophy-perhaps called “Bear Tracks” or “Pigment Spots” or “Retina Freckles”, it is important to carefully explore and review your family history with a Gastroenterologist who will likely schedule you for a colonoscopy. CHRPE has a “statistically significant” correlation with hereditary colon polyps known as Familial Adenomatous Polyposis, or FAP. It may be that the freckles are caused by the same genetic mutation that produces the polyps. A study published in 2010 in the American Journal of Gastroenterology concluded that patients with such freckles should be referred for colonoscopies.

Thus-when we are over 50 years of age, the reasons to have yearly eye exams includes not only detecting cataracts, glaucoma, age related macular degeneration (AMD) and other eye diseases, but regular eye examinations may very well be a reminder to be screened via colonoscopy to help detect early risks and potential indicators of colon cancer.

1 comment:

  1. Colon cancer is the third most prevalent cause of all cancer deaths. But colon cancer has an excellent cure rate if it's caught early. Learn what you can do to lower your risk.

    ceralin forte brain health

    ReplyDelete