Researchers from Rotterdam, Holland reported that women's risk of open-angle glaucoma (OAG) decreased significantly as body mass index (BMI) increased, according to data from their large cohort study. For every unit increase in body mass index, women had a 7% lower risk of glaucoma. Other lifestyle factors did not significantly influence either open-angle glaucoma or intraocular pressure (IOP) in men or women. Patients were categorized according to baseline values for socioeconomic status, education, smoking history, alcohol intake, and the measures of BMI and waist-to-hip ratio. Other studies of potentially modifiable risk factors for glaucoma have yielded mixed results, particularly with respect to obesity. Some studies have shown an inverse association between obesity and glaucoma but a positive association with IOP. The use of Goldmann applanation tonometry to assess intraocular pressure could have led to overestimation of values in obese women.
Archives of Ophthalmology:February 2011
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